7 Ways Bestie Balance Protects Your Dog's Body While They're on Long-Term Medication
Travis Rice
Jan 24, 2026
Medications do the job you need. But over time they put strain on the liver, gut, and inflammation response which causes other issues and weakens immunity. Here's how to keep their body in balance without feeling guilty about those medications anymore.
1. Your dog's liver never gets a day off
Their liver has to process every dose of Apoquel, every Cytopoint injection, every flea pill.
But when medication is daily or monthly for years, the liver is always working. No recovery window. Waste accumulates. The organ that's supposed to keep the system clean starts running behind.
How Bestie Balance helps:
Milk thistle supports liver function and helps keep liver enzyme numbers in a healthier range, reducing the downstream stress on the rest of the body.
2. Meds can wipe out a healthy gut biome
Every round of antibiotics wipes out gut bacteria good and bad alike.
The gut microbiome affects digestion, immune signaling, nutrient absorption, and inflammation regulation. When it's disrupted repeatedly, the body loses a key line of defense.
How Bestie Balance helps:
A 3-billion CFU probiotic blend helps rebuild beneficial bacteria faster, so the gut can stabilize before the next disruption.
Cleared up quickly!
"We're still on the first jar and Maggie's hot spots and ear yeast are almost gone. This worked faster than I tought"
3. Those "allergies" are usually inflammation or yeast coming from inside
When the liver can't clear waste fast enough, inflammation builds internally. The immune system stays on high alert. Skin becomes the pressure release valve. Shampoos and sprays treat the surface. They don't touch what's causing it.
How Bestie Balance helps:
By supporting the liver and gut directly, you address the source and not topicals or shampoos that only work for weeks at a time.
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4. You don't have to stop their medications, but their body does need support to stay in balance
Your dog's meds don't support the liver that processes them. They don't rebuild the gut bacteria they disrupt. They don't calm the inflammation they can't reach. That's not a flaw. It's just not what they're designed to do.
How Bestie Balance helps:
It fills the gap the medications leave behind: Liver support, gut repair, inflammation control so the body can handle the load.
Dr. Amanda DVM
5. Don't let me suffer from secondary issues like yeast
When the good bacteria in the gut is wiped out and inflammation is up, yeast can thrive. This fungus causes itching along with stinky ears & paws or even the brown stains under their eyes & on paws.
How Bestie Balance helps:
Chlorella binds to toxins to help the liver process them more quickly before they get to the skin causing itching
6. It's not too late to start
The liver and gut can recover function at any age. You're not undoing damage. You're giving the body what it needs to handle the daily load going forward.
How Bestie Balance helps:
The liver and gut respond to support regardless of age. Starting now means the body has help from here on out.
Linda M. with Cocker Spaniel
"My dog is 13 and has been on Apoquel since he was 9. I figured nothing would help at this point. After 6 weeks, he's more comfortable and actually wants to play again."
7. Give your dog better quality of life and give yourself peace of mind
Medications are sometimes a necessary part of your dog's life. You aren't managing a condition, you're protecting their long-term health while they're on it.
More consistent daily energy
Fewer flare ups
Less itching & skin issues
Better digestion
Bestie Balance ->
How Bestie Balance Works
When medications throw your dog's body out of whack, Bestie Balance helps get multiple systems back in alignment for less itching, tiredness and side effects.
Helps liver detox
Liver-cleansing herbs like milk thistle and dandelion root support detox pathways that eliminate yeast byproducts.
Restores gut balance
Probiotics crowd out bad bacteria and yeast, helping to reset your dog’s microbiome.
Alkalizes the body
Supergreens like chlorella and spirulina help reduce acidity, creating an environment where yeast struggles to thrive.
Fights inflammation inside and out
Antioxidants like Vitamin C and E help calm itchy, irritated skin caused by yeast overgrowth.
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Frequently Asked Questions
What are the ingredients?
Active Ingredients
Milk Thistle (150mg, 80% silymarin) — liver support
7-Strain Probiotic Blend (3 billion CFU) — gut balance
Omega-3s (200mg EPA/DHA) — inflammation
Chlorella (100mg) — toxin binding
Dandelion Root (75mg) — bile flow and waste removal
Zinc (15mg) and Vitamin E (30 IU) — skin repair
Vitamin C (25mg) — antioxidant support
Full ingredients can be found on the buying options on the next page. Click any button to see Bestie Balance buy options and full nutrition panel
Why are the doses higher than other supplements?
Most supplements use ingredient doses far below what's shown to be effective in studies. We use research-level doses. For example, 150mg of milk thistle instead of the 25-50mg you'll find in most products. That's why it works.
Where is it made?
Our products are proudly made in the USA.
Our manufacturing is in the midwest where we have a FDA inspected facility. It's also GMP-certified, and NASC certified.
We do third-party tested for purity and potency in all our products.
Which medications can I use this with?
Can I give this while my dog is on Apoquel? Yes. Bestie Balance supports the liver and gut systems that process Apoquel. It doesn't interfere with how the medication works.
Can I give this while my dog is on Cytopoint? Yes. Same answer — it supports the body's ability to handle the medication, not block it.
What about antibiotics? Yes, and this is especially useful during or after antibiotic treatment. Antibiotics disrupt gut bacteria. The probiotic blend helps rebuild what gets wiped out.
Can I give this with flea and tick medication (Nexgard, Bravecto, Simparica)? Yes. These medications are processed by the liver. Bestie Balance supports liver function.
My dog is on multiple medications. Is that okay? Yes. Dogs on multiple meds often benefit the most because the cumulative processing load is higher.
Should I check with my vet first? If you want to, yes. We're happy to send your vet the full ingredient list and doses. But there's nothing in Bestie Balance that interferes with common veterinary medications.
What flavor and do dogs like it?
These are peanut butter flavored, and we found 97% of dogs will eat these if given.
Note: Since we do use high concentration, this may be off-putting to a few dogs, if so try giving with peanut butter, yogurt, or broken over they meals until they get used to the smell and flavor.
My dog just finished antibiotics and their gut is a mess. How fast will this help?
Gut issues after antibiotics usually improve within 7-10 days. Stool firms up first, then ear/yeast issues start to resolve.
Does this work as a liver support supplement?
Yes Bestie Balance can replace most liver support supplements. We use 80% silymarin, whereas most liver supplements use a diluted powder.
Part of the value of Bestie Balance is you are getting a full liver supplement, a full probiotic supplement, and an anti-itch supplement in one. If bought by themselves, that would be at least $87 together.
I've seen this advertised for yeast before, why?
Yeast is one of the symptoms Bestie Balance is best at helping with. Because yeast builds in the gut and get to the skin because of delayed detoxing.
Bestie Balance is a wholehistic approach to fighting off yeast compared to topicals that only help flare ups, or probiotics which only help the gut.
Is this the same as a probiotic supplement?
No. Probiotics are one component. Bestie Balance also includes liver support (milk thistle, dandelion root), anti-inflammatory support (omega-3s), and skin healing support (zinc, vitamin E). It's designed specifically for dogs under medication load, not just general gut health.
Is it safe for older dogs?
Yes. The ingredients are gentle and well-tolerated. If your senior dog has specific health conditions beyond allergies/skin issues, check with your vet.
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From our family to yours
We’re a family-run business in Colorado committed to helping your dog live better, for longer.
We know firsthand how hard it is to find products that truly benefit your pet’s health.
Many products on the market contain artificial ingredients and fillers – or use good ingredients in tiny amounts.
That’s why we created Kayode: to bring you supplements made with natural, science-backed ingredients that genuinely support your dog’s health and happiness.
Developed in Colorado
Approved By Vets
All-Natural Ingredients
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This is an advertisement for Kayode and is intended for informational purposes only. All information provided by Kayode does not constitute medical advice and should not be used as a replacement for veterinarian advice.
Please consult your veterinarian regarding any change in treatment or supplementation.
The views and opinions expressed are solely those of Kayode or a testimonial from a verified Kayode customer based on his/her real-life experiences. Individual results may vary. While many of Kayode testimonials are unsolicited, some consumers received compensation in return for an honest review.
Please note that Kayode products are not drugs and are not intended to treat, prevent, or cure any disease.
